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Translational development of CRMA-1001, an epigenetic silencer for the treatment of chronic hepatitis B
May 12, 2026
ASGCT Conference
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Establishment of assay limits for differential gene expression and DNA methylation to characterize specificity of epigenetic editing
November 10, 2025
AASLD Conference
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Epigenetic editors targeting chronic Hepatitis B achieve HBV surface antigen loss with a single course of treatment in multiple HBV mouse models
November 7, 2025
AASLD Conference
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Integrated epigenetic and genetic programming of primary human T cells
September 9, 2025
Nature Biotechnology
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Efficient and Liver-Detargeted In Vivo Multiplex Gene Editing of Human Hematopoietic Stem and Progenitor Cells
May 14, 2025
ASGCT Conference
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Engineered Virus-Like Particles with Minimal Viral Components for Improved Base Editing Efficiency In Vivo
May 14, 2025
ASGCT Conference
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E4/K4 Coiled-Coils Improve Cargo Loading in Engineered Virus-like Particles
May 14, 2025
ASGCT Conference
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A novel PCSK9 Epigenetic Editor Achieves Maximal Pharmacology with Best-in-class Potency in Non-human Primates
May 4, 2025
EAS 93rd Congress
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CRMA-1001 an epigenetic editor for the treatment of chronic hepatitis B
March 21, 2025
Global Hepatitis Summit 2025
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A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels
February 10, 2025
Nature Medicine